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Retrogenesis : ウィキペディア英語版
Retrogenesis

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Retrogenesis (also known as retro-genesis) is a medical term used to describe a scientific hypothesis about the development and progress of Alzheimer's disease (AD), an affliction that features variety of severe symptoms relating to brain function. Human neuro-pathological studies have determined that AD impairs tens of millions of people worldwide, with cognitive abilities suffering in victims as the structure of minute tissues within their brain becomes altered. Giving the victims the best, most effective care has been seen as a difficult issue given the radically negative changes that AD can cause in people's life skills. The retrogenesis hypothesis assumes that white matter atrophy takes place within the human nervous system, changes such as myelin breakdown and axonal damage taking place.〔("Integrating Retrogenesis Theory to Alzheimer’s Disease Pathology: Insight from DTI-TBSS Investigation of the White Matter Microstructural Integrity" ). BioMed Research International Volume 2015 (2015), Article ID 291658, 11 pages ( http://dx.doi.org/10.1155/2015/291658 )〕〔
While research is ongoing and findings are under dispute, multiple studies have remarked that individuals find that the loss of life skills, memory related abilities, and general engagement with intellectual pursuits associated with Alzheimer's disease feature an odd parallel to the personal growth that in infants and children. The atrophy on the one side and development on the other side, as the retrogenesis hypothesis goes, seems to follow the same steps yet in opposite order.〔〔Reisberg, B, Frannsen E, Souren L, Liduin EM, Auer
S, Akram I, Kenowsky S. ("Evidence and mechanisms of retrogenesis in Alzheimer’s and other dementias: Management and treatment import" ). ''American Journal of Alzheimer’s Disease and Other Dementias.'' 2002; 17: 206.〕
==Research details==

One article looking into the matter in 2002, published by the ''American Journal of Alzheimer's Disease & Other Dementias'', found that "the stages of AD can be translated into corresponding developmental ages (DAs)" as well as that "these DAs can account for the overall management and care needs of AD patients." The study also concluded, "A science of AD management can be formulated on the basis of the DA of the Alzheimer's patient, taking into consideration differences of AD from normal development as well as homologies."〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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