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Rhazinilam : ウィキペディア英語版
Rhazinilam

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Rhazinilam is an alkaloid first isolated in 1965 by Linde from the ''Melodinus australis'' plant. It was later isolated from ''Rhazya stricta'' as well as from other sources.
==Biological activity==
Rhazinilam has activity similar to that of colchicine, taxol and vinblastine, acting as an inhibitor of the tubulin-microtubules equilibrium.
==Total synthesis==
Rhazinilam was first synthesized in 1973 by Smith and coworkers, and multiple subsequent times.
===Trauner synthesis===
Rhazinilam was synthesized by the Trauner group in 2005.
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