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Risperidone ( ) (trade name Risperdal and generics) is an antipsychotic drug mainly used to treat schizophrenia (including adolescent schizophrenia), schizoaffective disorder, the mixed and manic states of bipolar disorder, and irritability in people with autism. Risperidone is a second-generation atypical antipsychotic. It is a dopamine antagonist possessing anti-serotonergic, anti-adrenergic and anti-histaminergic properties. Adverse effects of risperidone include significant weight gain and metabolic problems such as diabetes mellitus type 2, as well as tardive dyskinesia and neuroleptic malignant syndrome. There is evidence that risperidone and other antipsychotics produce "a small increase in the risk of death" in people with dementia, though prescription "should be considered in a wider medical context." The drug was developed by Janssen-Cilag, subsidiary of Johnson & Johnson, from 1988 to 1992 as an improvement from the typical antipsychotic and first approved by the FDA in 1994.〔(Risperdal (risperidone) at naminh.org/resources ) (web archive)〕 Today many generic versions are available. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. ==Medical uses== Risperidone is used for the treatment of schizophrenia, bipolar disorder also including behavior problems in autistic people.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/risperidone.html )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Risperidone」の詳細全文を読む スポンサード リンク
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