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・ RNSAP
・ RNSP
・ RNB Global University
・ RNB Research
・ RNC
・ RNC 8
・ RNC Media
・ RNC Welcoming Committee
・ RncO
・ RNCP
・ RND
・ Rnd
・ Rnd (GTPase)
・ Rnd1
・ Rnd2
Rnd3
・ RNDC (Republic National Distributing Company)
・ RNDeer
・ RNDF
・ RNDIS
・ RNDM
・ RNDP
・ RNDr
・ RNE Radio 3
・ RNE Radio 5
・ RNE Radio Clásica
・ RNE Radio Nacional
・ RNE Ràdio 4
・ Rne-II RNA motif
・ RNF10


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Rnd3 : ウィキペディア英語版
Rnd3

Rnd3 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND3.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=390 )
Like other members of the Rho family of Ras-related GTPases it regulates the organization of the actin cytoskeleton in response to extracellular growth factors.
==Regulation==
Like Ras, Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925); GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855); and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998).(by OMIM )〔


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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