|
C677T or Rs1801133 is a genetic variation—a single nucleotide polymorphism (SNP)—in the ''MTHFR'' gene. Among Americans the frequency of T-homozygosity ranges from 1% or less among Blacks to 20% or more among Italians and Hispanics. It has been related to * schizophrenia * Alzheimer's disease * depression * autism * spina bifida.〔 In 2000 association studies on oral clefts, Down syndrome, and fetal anticonvulsant syndrome were either unreplicated or had yielded conflicting results.〔 == Related genetic variants == A1298C is a SNP in the same gene. Studies have investigated the combined effect of C677T and A1298C. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Rs1801133」の詳細全文を読む スポンサード リンク
|