翻訳と辞書 Words near each other ・ S19 ・ S19 Xinnong–Jinshanwei Expressway ・ S190 ・ S1909/A2840 ・ S1B reactor ・ S1C ・ S1C reactor ・ S1G reactor ・ S1ngles ・ S1P ・ S1PR1 ・ S1PR2 ・ S1PR3 ・ S1PR4 ・ S1PR5 ・ S1RA ・ S1W ・ S1W reactor ・ S2 ・ S2 (Berlin) ・ S2 (classification) ・ S2 (missile) ・ S2 (Munich) ・ S2 (Nuremberg) ・ S2 (programming language) ・ S2 (Rhine-Main S-Bahn) ・ S2 (Rhine-Ruhr S-Bahn) ・ S2 (star) ・ S2 (TV channel) ・ S2 (ZVV) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク S1RA ： ウィキペディア英語版 S1RA S1RA, E-52862, or 4-(2-((5-methyl-1-(naphthalen-2-yl)-1''H''-pyrazol-3-yl)oxy)ethyl)morpholine is a selective sigma-1 receptor antagonist, with a reported binding affinity of ''K''i = 17.0 ± 7.0 nM, selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. In preclinical studies, S1RA has demonstrated efficacy in relieving neuropathic pain and pain in other sensitizing conditions, associated with an improvement of the emotional negative state. S1RA is being developed by Esteve for the treatment of neuropathic pain and the potentiation of opioid analgesia and has successfully completed Phase I clinical trials showing good safety and tolerability, and a pharmacokinetic profile compatible with once a day oral administration. Phase II clinical trials are currently underway, making S1RA the first selective sigma-1 receptor antagonist evaluated in humans for these conditions. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「S1RA」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.