翻訳と辞書 |
S33005
S33005 is a serotonin–norepinephrine reuptake inhibitor (SNRI) that was under development by Servier for the treatment of depression and related disorders. It is structurally related to venlafaxine but has a more complex molecular structure. It is not known if this compound acts as a sigma agonist, although for venlafaxine, apparently it appears that this is indeed the case. ==Synthesis== "The 1-cyano-benzocyclobutenes used as starting material are obtained, for example, by subjecting a β-()-propionitrile to intramolecular condensation in the presence of potassium amide, or by brominating a benzocyclobutene in position 1 with ''N''-bromosuccinimide, followed by exchange of the bromine atom for a cyano group by means of sodium cyanide."
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「S33005」の詳細全文を読む
スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|