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・ Sar-e Pol city
・ Sar-e Pol District
・ Sar-e Pol Province
・ Sar-e Pol, Golestan
・ Sar-e Pol, Kerman
・ Sar-e Pol, South Khorasan
・ Sar-e Pol, Zanjan
・ Sar-e Razg
・ Sar-e Sal
・ Sar-El
・ Sar-i Sang
・ Sar-I-Ab railway station
・ Sar-I-Bolan railway station
・ SAR-Lupe
・ Sar-Tov Stadium
SAR1A
・ SAR1B
・ SAR201
・ Sara
・ Sara (1992 film)
・ Sara (2015 film)
・ Sara (artist)
・ Sara (band)
・ Sara (Belgian TV series)
・ SARA (computer)
・ Sara (Fleetwood Mac song)
・ Sara (Starship song)
・ Sara (U.S. 1976 TV series)
・ Sara (U.S. 1985 TV series)
・ Sara Adler


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SAR1A : ウィキペディア英語版
SAR1A

SAR1A or Sar1 is a protein involved in membrane trafficking. It is a GTPase found in COPII vesicles. It regulates the assembly and disassembly of COPII coats.
GDP-bound Sar1 interacts with the membrane-bound exchange factor Sec12 and exchanges its bound GDP for GTP. The hydrophobic N-terminus of Sar1-GTP then locates it to the membrane, where it serves as the binding site for the Sec23/Sec24 protein coat complex. After the vesicle coat is completely assembled and the vesicle is released from the donor membrane, the Sec23 subunit promotes Sar1 GTPase activity, which triggers the disassembly of the COPII coat.
==See also==

*ARF

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「SAR1A」の詳細全文を読む



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