翻訳と辞書 Words near each other ・ Serpico (disambiguation) ・ Serpico (TV series) ・ Serpierite ・ Serpiginous ・ Serpiginous choroiditis ・ Serpil ・ Serpil Hamdi Tüzün ・ Serpil İskenderoğlu ・ Serpil Timuray ・ Serpil Yassıkaya ・ Serpin ・ SERPINA2 ・ Serpina3f ・ SERPINA4 ・ SERPINA9 ・ SERPINB1 ・ SERPINB10 ・ SERPINB13 ・ SERPINB3 ・ SERPINB4 ・ SERPINB6 ・ SERPINB7 ・ SERPINB8 ・ SERPINB9 ・ SERPINE2 ・ SERPINI1 ・ SERPINI2 ・ Serpis ・ Serpmyxis ・ Serpon Sugar Mill Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク SERPINB1 ： ウィキペディア英語版 SERPINB1 Leukocyte elastase inhibitor (LEI) also known as serpin B1 is a protein that in humans is encoded by the ''SERPINB1'' gene. It is a member of the clade B serpins or ov-serpins (ovalbumin related serpins) founded by ovalbumin.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1992 )〕 MNEI (murine neutrophil elastase inhibitor) is the mouse orthologue of human SerpinB1.〔 == Function == SerpinB1 is a cytoplasmic serine protease inhibitor of polymorphonuclear neutrophils. Among other serine proteases, it specifically inhibits neutrophil elastase, PR3 and cathepsin G, all found in neutrophil granules, by a suicide inhibition mechanism. SerpinB1 was found to reduce tissue damage caused by the mentioned proteases during inflammation and has a role in neutrophil homeostasis in mice. In various infection models (e.g. pneumonia) correlation of SerpinB1 absence and lack of microbial clearance have been shown. Different knockout strains serve as model to investigate the role of SerpinB1 in vivo.〔〕〔〕〔〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「SERPINB1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.