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・ Sgt. Pepper's Lonely Hearts Club Band (song)
・ Sgt. Pepper's Lonely Hearts Club Band (soundtrack)
・ SGCB
・ SGCC UAV
・ SGCD
・ SGCE
・ SGCG
・ SGCZ
・ SGD (disambiguation)
・ SGE
・ SGE Analytical Science
・ SGE Group
・ SGE Loans
・ Sge2d
・ SGEduLab
SGEF
・ Sgeotasaigh
・ SGES
・ SGF
・ SGG
・ SGGS
・ SGH
・ SGH War Memorial
・ Sghair Ould M'Bareck
・ SGHC
・ SGHS
・ SGI
・ SGI 1600SW
・ SGI algorithm
・ SGI Altix 350


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SGEF : ウィキペディア英語版
SGEF

SGEF (Src homology 3 domain-containing Guanine nucleotide Exchange Factor) is a 97 kDa protein involved in intracellular signalling networks. It functions as a guanine nucleotide exchange factor (GEF) for RhoG, a small G protein of the Rho family.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26084&ordinalpos=1&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum )
==Discovery==
SGEF was discovered during a screen for androgen-responsive genes in human prostate cancer cells. Subsequent northern blot analysis revealed expression of SGEF in tissues of the heart, brain, placenta, lung, liver, kidney, pancreas, prostate, testis, small intestine and colon. SGEF is also expressed in endothelial cells of the vasculature. Several widely used cell lines express this protein, these include A431, HeLa, HUT78, HEK-293, Jurkat, THP, PC12, RAJI, U937 and Meg-01.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「SGEF」の詳細全文を読む



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