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Serine/threonine-protein kinases SGK represent a kinase subfamily with orthologs found across animal clades and in yeast (compare (Treefam family TF320906 )). In most vertebrates, including humans, there are three isoforms encoded by the genes ''SGK1'', ''SGK2'', and ''SGK3''. The name Serum/glucocorticoid-regulated kinase refers to the first cloning of a SGK family member from a cDNA library screen for genes upregulated by the glucocorticoid dexamethasone in a rat mammary epithelial tumor cell line. The first human family member (human ''SGK1'') was cloned in a screen of hepatocellular genes regulated in response to cellular hydration or swelling. The term SGK is also used as a synonym for ''SGK1''.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6446 )〕 == Function == (詳細はmyo-inositol transporter during osmotic stress. Deregulated expression of SGK1 in the endometrium has been implicated in cases of infertility or recurrent miscarriage in humans, and SGK1 expression in the endometrium also affects fertility in mice. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「SGK」の詳細全文を読む スポンサード リンク
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