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SGOL1
Shugoshin-like 1 is a protein that in humans is encoded by the ''SGOL1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=151648 )〕 ==Model organisms==
Model organisms have been used in the study of SGOL1 function. A conditional knockout mouse line, called ''Sgol1tm1a(EUCOMM)Wtsi'' has been generated. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty six tests were carried out on mutant mice and three significant abnormalities were observed. No homozygous mutant embryos were identified during gestation, and thus none survived until weaning. The remaining tests were carried out on heterozygous mutant adult mice and a decreased regulatory T cell number was observed in male animals.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「SGOL1」の詳細全文を読む
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