翻訳と辞書 |
SH3D21
SH3D21 is a nuclear protein that is encoded by the SH3D21 gene. In humans, this gene is located on chromosome 1 p34.3.〔 The human mRNA transcript is 2527 base pairs and the final protein product is 756 amino acids.〔 While the exact function of this protein remains unknown, due to the presence of three SH3 domains, it has been implicated in protein-protein interactions.〔 == Gene ==
SH3D21 is expressed in low levels in most tissue.〔 Microarray analysis has shown SH3D21 expression to be decreased in TP63 knockout mice.〔(【引用サイトリンク】 url=http://www.ncbi.nlm.nih.gov/geo/tools/profileGraph.cgi?ID=GDS1435:162779_i_at )〕 SH3D21 has been shown to be expressed highly in the superior cervical ganglion, the dorsal root ganglia and the trigeminal ganglion.〔(【引用サイトリンク】url=http://biogps.org/#goto=genereport&id=79729 )〕〔(【引用サイトリンク】url=http://www.ncbi.nlm.nih.gov/geo/tools/profileGraph.cgi?ID=GDS596:220193_at )〕 Transcription of SH3D21 is known to be upregulated in the presence of testosterone.〔(【引用サイトリンク】 url=http://rgd.mcw.edu/rgdweb/report/annotation/table.html?term=CHEBI:17347&id=1312915 )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「SH3D21」の詳細全文を読む
スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|