翻訳と辞書 Words near each other ・ Shaznay Lewis discography ・ Shazuan Ashraf Mathews ・ Shazz ・ Shazza ・ Shazza McKenzie ・ Shazzan ・ Shazzy Fitness ・ Shaʿrānī ・ SHB ・ SHB (gene) ・ SHB Da Nang F.C. ・ SHB Vientiane F.C. ・ SHBT ・ SHC ・ Shc the shell script compiler ・ SHC1 ・ SHC2 ・ SHC3 ・ SHCBP1 ・ SHCC ・ Shcha ・ Shchara River ・ Shchaslyve ・ Shchaslyvtseve ・ Shchastya ・ Shchastya Bay ・ Shche ne vmerla Ukraina ・ Shchedrin ・ Shchedryk ・ Shchedryk (choir) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク SHC1 ： ウィキペディア英語版 SHC1 SHC-transforming protein 1 is a protein that in humans is encoded by the ''SHC1'' gene. SHC has been found to be important in the regulation of apoptosis and drug resistance in mammalian cells. SCOP classifies the 3D structure as belonging to the SH2 domain family. == Gene and expression == The gene SHC1 is located on chromosome 1 and encodes 3 main protein isoforms: p66SHC, p52SHC and p46SHC. These proteins differ in activity and subcellular locations, p66 is the longest and while the p52 and p46 link activated receptor tyrosine kinase to the RAS pathway.〔(【引用サイトリンク】title= Genes and Mapped Phenotypes )〕 The protein SHC1 also acts as a scaffold protein which is used in cell surface receptors. The three proteins that SHC1 codes for have distinctly different molecular weights. All three SHC1 proteins share the same domain arrangement consisting of an N-terminal phosphotyrosine-binding(PTB) domain and a C-terminal Src-homology2(SH2) domain. Both of the domains for the three proteins can bind to tyrosine-phosphorylated proteins but they are different in their phosphopeptide-binding specificities. P66SHC is characterized by having an additional N-terminal CH2 domain.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「SHC1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.