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・ Sigma Gamma Rho
・ Sigma Gamma Tau
・ Sigma Geminorum
・ Sigma Guitars
・ Sigma Harmonics
・ Sigla himinfley
・ Siglap
・ Siglap MRT Station
・ Siglap Secondary School
・ Siglap Single Member Constituency
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SIGLEC8
・ SIGLEC9
・ Sigleif Johansen
・ Sigler
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・ Sigleß
・ Sigli
・ Siglin Rocks
・ Siglind Bruhn
・ Siglinde Kallnbach
・ Siglingasamband Íslands
・ Siglistorf
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・ Siglitun
・ Siglo Veintiuno


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SIGLEC8 : ウィキペディア英語版
SIGLEC8

Sialic acid-binding Ig-like lectin 8 is a protein that in humans is encoded by the ''SIGLEC8'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27181 )〕 This gene is located on chromosome 19q13.4, about 330 kb downstream of the SIGLEC9 gene.〔 Within the siglec family of transmembrane proteins, Siglec-8 belongs to the CD33-related siglec subfamily, a subfamily that has undergone rapid evolution.
==Initial characterization==

Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2).〔〔
At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney.〔


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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