翻訳と辞書 Words near each other ・ Sis, Kurdistan ・ Sisa ・ Sisa Koyamaibole ・ Sisa Waqa ・ Sisaala language ・ Sisab ・ Sisabad ・ Sisabanibadahara ・ Sisahaniya ・ Sisahaniya, Narayani ・ Sisahaniya, Rapti ・ Sisai ・ Sisai (Vidhan Sabha constituency) ・ Sisai block ・ Sisai, Hisar ・ SIRT6 ・ SIRT7 ・ Sirtaki ・ Sirtaki (album) ・ Sirte ・ Sirte (disambiguation) ・ Sirte Basin ・ Sirte Declaration ・ Sirte District ・ Sirte Oil Company ・ Sirte Stadium ・ Sirte University ・ Sirtex ・ Sirthouli ・ Sirtir Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク SIRT6 ： ウィキペディア英語版 SIRT6 Sirtuin-6 (SIRT6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51548 )〕 SIRT6 functions in multiple molecular pathways related to aging, including DNA repair, telomere maintenance, glycolysis and inflammation.〔 == Function == Studies in mice have revealed that Sirt6 is essential for post-natal development and survival. Sirt6 knock-out mice, in which the gene encoding Sirt6 has been disrupted, exhibit a severe progeria, or premature aging syndrome, characterized by spinal curvature, greying of the fur, lymphopenia and low levels of blood glucose. The lifespan of Sirt6 knock-out mice is typically one to three months, dependent upon the strain in which the Sirt6 gene has been deleted. By contrast, wild type mice, which retain expression of Sirt6, exhibit a maximum lifespan of two to four years.〔 Mice which have been genetically engineered to overexpress, or produce more, Sirt6 protein exhibit an extended maximum lifespan. This lifespan extension, of about 15-16 percent, is observed only in male mice. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「SIRT6」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.