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SKBR3
SkBr3 is a cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970. It was derived from a pleural effusion due to an adenocarcinoma originating in the breast of a 43-year-old, caucasian female. The cell line over-expresses the HER2 gene product. 〔(【引用サイトリンク】url=http://www.lgcstandards-atcc.org/LGCAdvancedCatalogueSearch/ProductDescription/tabid/1068/Default.aspx?ATCCNum=HTB-30&Template=cellBiology )〕 The SkBr3 line is synonymous(derived from the same patient) with the AU565 cell line.〔(【引用サイトリンク】url=http://cancer.lbl.gov/breastcancer/viewline.php?id=4 )〕 The SkBr3 cell line has been used in studies seeking to overcome Herceptin resistance to HER2-overexpressing breast cancer.〔(【引用サイトリンク】url=http://molpharm.aspetjournals.org/content/70/5/1534.full )〕 The cells are considered biosafety level 1.〔 ==References==
==External links== *(Cellosaurus entry for SkBr3 )
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「SKBR3」の詳細全文を読む
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