翻訳と辞書 Words near each other ・ SLC1A5 ・ SLC20A1 ・ SLC20A2 ・ SLC22A1 ・ SLC22A10 ・ SLC22A11 ・ SLC22A12 ・ SLC22A18 ・ SLC22A2 ・ Slc22a21 ・ SLC22A25 ・ SLC22A3 ・ SLC22A4 ・ SLC22A5 ・ SLC22A7 ・ SLC22A8 ・ SLC22A9 ・ SLC23A1 ・ SLC23A2 ・ SLC24A4 ・ SLC24A5 ・ SLC25A1 ・ SLC25A10 ・ SLC25A11 ・ SLC25A12 ・ SLC25A14 ・ SLC25A16 ・ SLC25A17 ・ SLC25A19 ・ SLC25A21 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク SLC22A8 ： ウィキペディア英語版 SLC22A8 Solute carrier family 22 member 8, or organic anion transporter 3 (OAT3), is a protein that in humans is encoded by the ''SLC22A8'' gene. == Function == OAT3 is involved in the transport and excretion of organic ions some of which are drugs (e.g., penicillin G (benzylpenicillin), methotrexate (MTX), indomethacin (an NSAID), and ciprofloxacin (a fluoroquinolone antibiotic)) and some of which are pure toxicants.〔 SLC22A8 (OAT3) is indirectly dependent on the inward sodium gradient, which is a driving force for reentry of dicarboxylates into the cytosol. Dicarboxylates, such as alpha-ketoglutarate generated within the cell, or recycled from the extracellular space, are used as exchange substrates to fuel the influx of organic anions against their concentration gradient. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of renal proximal tubule cells.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「SLC22A8」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.