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・ SMBC Insight
・ SMBH
・ SMBH, Inc.
・ SMBRelay
・ SMC
・ SMC connector
・ SMC Corporation
・ SMC Global Securities Limited
・ SMC Hickton Madeley Architects
・ SMC Lähiörotat
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・ Smc Pentax D FA 645 55mm F2.8 AL (IF) SDM AW
・ Smc Pentax-D FA 645 25mm F4 AL (IF) SDM AW
・ SMC protein
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SMC1A
・ SMC1B
・ SMC2
・ SMC3
・ SMC4
・ SMC5
・ SMC6
・ SMCC
・ SMCET - Engineering College in Jaipur
・ SMCP
・ SMCR2
・ SMCR7L
・ SMCRA
・ SMD
・ SMD High School


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SMC1A : ウィキペディア英語版
SMC1A

Structural maintenance of chromosomes protein 1A is a protein that in humans is encoded by the ''SMC1A'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8243 )
== Function ==

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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