翻訳と辞書 Words near each other ・ Sorolopha stygiaula ・ Soroly ・ Soromaya ・ Sorombo ・ Soromonichthys stearleyi ・ Soron ・ Sorona ・ Sorond ・ Sorkočević (family) ・ Sorkuh ・ Sorkun ・ Sorkun, Sandıklı ・ Sorkunlu, Aydıntepe ・ Sorkvareh Owlad Qobad ・ Sorkwity ・ SORL1 ・ Sorlaci ・ Sorlada ・ Sorlagondi ・ Sorley ・ Sorley (given name) ・ Sorley (surname) ・ Sorley Boy MacDonnell ・ Sorley MacLean ・ Sorlie Memorial Bridge ・ Sorlin ・ Sorliney ・ Sorlle Buttress ・ Sorlle Rocks ・ SORM Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク SORL1 ： ウィキペディア英語版 SORL1 Sortilin-related receptor, L(DLR class) A repeats containing is a protein that in humans is encoded by the SORL1 gene. SORL1 (also known as SORLA, SORLA1, or LR11) is a neuronal apolipoprotein E receptor, the gene for which is predominantly expressed in the central nervous system. == Clinical significance == Mutation of the gene for apolipoprotein E (APOE) is predictive of Alzheimer's disease. Lack of the APOE receptor is suspected to be a contributory factor to Alzheimer's: a significant reduction in ''SORL1'' (''LR11'') expression has been found in brain tissue of Alzheimer's disease patients. The APOE receptor has also been linked with regulation of amyloid precursor protein, faulty processing of which is implicated in Alzheimer's. A more recent study by a group of international researchers 〔 ''Advance online publication; Volume/Issue/Page available later''〕 supports the proposition that ''SORL1'' plays a part in seniors developing Alzheimer's disease, the findings being significant across racial and ethnic strata. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「SORL1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.