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SPPL2A
Signal peptide peptidase-like 2A, also known as SPPL2A, is a human gene.〔 == Function ==
This gene is a member of the signal peptide peptidase-like protease (SPPL) family and encodes an endosomal membrane protein with the conserved active site motifs 'YD' and 'GxGD' in adjacent transmembrane domains (TMDs). This protein plays a role in innate and adaptive immunity by cleaving TNFα in activated dendritic cells. A pseudogene of this gene also lies on chromosome 15.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84888 )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「SPPL2A」の詳細全文を読む
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