翻訳と辞書 Words near each other ・ St Aidan's and St John Fisher Associated Sixth Form ・ St Aidan's Anglican Church, Johannesburg ・ St Aidan's Anglican Girls' School ・ St Aidan's Catholic Academy ・ St Aidan's Church of England Academy ・ SSPT ・ SSPTV ・ SSPX (disambiguation) ・ SSPX Resistance ・ SSPX-affiliated religious orders ・ SSQ ・ SSQ (band) ・ SSQ Financial Group ・ SSR ・ SSR Engineering College ・ SSR-180,575 ・ SSR-180,711 ・ SSR1 ・ SSR2 ・ SSR4 ・ SSRA ・ SSRC ・ SSRG ・ SSRI (disambiguation) ・ SSRL ・ SSRM ・ SSRS ・ SSS ・ SSS (cipher) ・ SSS islands Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク SSR-180,575 ： ウィキペディア英語版 SSR-180,575 SSR-180,575 is a drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It has been shown to have neuroprotective and cardioprotective effects and to stimulate steroidogenesis of pregnenolone in the brain, which may be linked to its neuroprotective action.〔Ferzaz B, Brault E, Bourliaud G, Robert JP, Poughon G, Claustre Y, Marguet F, Liere P, Schumacher M, Nowicki JP, Fournier J, Marabout B, Sevrin M, George P, Soubrie P, Benavides J, Scatton B. SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino()indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair. ''Journal of Pharmacology and Experimental Therapeutics''. 2002 Jun;301(3):1067-78. PMID 12023539〕〔Leducq N, Bono F, Sulpice T, Vin V, Janiak P, Fur GL, O'Connor SE, Herbert JM. Role of peripheral benzodiazepine receptors in mitochondrial, cellular, and cardiac damage induced by oxidative stress and ischemia-reperfusion. ''Journal of Pharmacology and Experimental Therapeutics''. 2003 Sep;306(3):828-37. PMID 12928523〕〔Kunduzova OR, Escourrou G, De La Farge F, Salvayre R, Séguélas MH, Leducq N, Bono F, Herbert JM, Parini A. Involvement of peripheral benzodiazepine receptor in the oxidative stress, death-signaling pathways, and renal injury induced by ischemia-reperfusion. ''Journal of the American Society of Nephrology''. 2004 Aug;15(8):2152-60. PMID 15284300〕〔Veenman L, Gavish M. The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development. ''Pharmacology and Therapeutics''. 2006 Jun;110(3):503-24. PMID 16337685〕 == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「SSR-180,575」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.