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STAT4
STAT4 is a transcription factor belonging to the Signal Transducer and Activator of Transcription protein family. It is required for the development of Th1 cells from naive CD4+ T cells and IFN-γ production in response to IL-12. == Structure ==
Human as well murine STAT4 genes lie next to STAT1 gene locus suggesting that the genes arose by gene duplication.〔 STAT proteins have several functional domains, including an N-terminal interaction domain, a central DNA-binding domain, an SH2 domain, and the C-terminal transactivation domain.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「STAT4」の詳細全文を読む
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