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Salvestrol
A salvestrol is a natural, dietary phytochemical that can be converted into a cytotoxic metabolite by Cytochrome P450 enzymes that are overexpressed by cancer cells.〔Tan, H. L. et al (2007). ("Salvestrols–natural anticancer prodrugs in the diet" ). ''Journal of Pharmacy and Pharmacology,'' 59(S1):A-59–A-63. doi:(10.1211/002235707781850122 ).〕 The name "salvestrols" was coined by Gerald Potter.〔Ware, W. R. (2009). "Nutrition and the Prevention and Treatment of Cancer: Association of Cytochrome P450 CYP1B1 With the Role of Fruit and Fruit Extracts". ''Integrative Cancer Therapies'', 8(1):22–28. doi:(10.1177/1534735408328573 ).〕 "Salvestrol" has been trademarked and is used to market dietary supplements and other products.〔(【引用サイトリンク】title=SALVESTROL UK00002375611 )〕 Some salvestrol-based products contain extracts from blackcurrant, blueberry, strawberry, and tangerine peel.
== Initial public reception ==
On January 1, 2005 ''The Observer'' reported that "salvestrols" had been chosen as one of the "20 big ideas" of that year.〔("20 big ideas" ). ''The Observer''. Saturday, January 1, 2005. Retrieved December 1, 2013.〕 A 2007 BBC News story reported on a laboratory study that had found salvestrols extracted from tangerine peel showing anti-cancer effects. Commenting on this a spokesperson from Cancer Research UK said, "while this research shows that salvestrols have an effect on cells in the laboratory, there is no evidence that they have a similar effect in patients".
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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