翻訳と辞書 Words near each other ・ Sarcoid ・ Sarcoidosis ・ Sarcolaena ・ Sarcolaena codonochlamys ・ Sarcolaena delphinensis ・ Sarcolaena eriophora ・ Sarcolaena grandiflora ・ Sarcolaena humbertiana ・ Sarcolaena isaloensis ・ Sarcolaena multiflora ・ Sarcolaena oblongifolia ・ Sarcolaenaceae ・ Sarcolemma ・ Sarcoleotia ・ Sarcolestes ・ Sarcolipin ・ Sarcolobus ・ Sarcolobus globosus ・ SARCOM ・ Sarcoma ・ Sarcoma botryoides ・ Sarcoman ・ Sarcomastigophora ・ Sarcomatoid carcinoma ・ Sarcomatoid carcinoma of the lung ・ Sarcomelicope ・ Sarcomelicope glauca ・ Sarcomelicope simplicifolia ・ Sarcomere ・ Sarcomphalus Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Sarcolipin ： ウィキペディア英語版 Sarcolipin Sarcolipin is a protein that in humans is encoded by the ''SLN'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6588 )〕 == Function == Sarcoplasmic reticulum Ca2+-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca2+ from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca2+-ATPases. The transmembrane protein interacts with Ca2+-ATPases and reduces the accumulation of Ca2+ in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6588 )〕 Ablation of sarcolipin increases atrial Ca2+ transient amplitudes and enhanced atrial contractility. Furthermore, atria from sarcolipin-null mice have blunted response to isoproterenol stimulation, implicating sarcolipin as a mediator of beta-adrenergic responses in atria. Recently it has been shown that SLN is an important mediator of muscle based thermogenesis and loss of sarcolipin predisposes mice to diet-induced obesity thus suggesting its role in energy metabolism and regulation of weight gain 〔Bal NC, Maurya SK, Sopariwala DH, Sahoo SK, Gupta SC, Shaikh SA, Pant M et al.: Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals. Nat Med, 2012. http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.2897.html〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Sarcolipin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.