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Secretagogin : ウィキペディア英語版
Secretagogin

Secretagogin is a protein that in humans is encoded by the ''SCGN'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10590 )
== Function ==

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in potassium chloride-stimulated calcium flux and cell proliferation.〔 This protein plays an important role in the release of the stress hormone Corticotropin-releasing hormone (CRH) and which only then enables stress processes in the brain. SCGN, in addition to Calcium ions, can bind Magnesium ions with moderate affinity. Ca2+-binding induces partial dimerization of SCGN ''in vitro''.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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