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Selamectin : ウィキペディア英語版
Selamectin

Selamectin (trade names Revolution, Stronghold) is a topical ancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration = Topical

| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =

| CAS_number_Ref =
| CAS_number = 220119-17-5
| CAS_supplemental =
| ATCvet = yes
| ATC_prefix = P54
| ATC_suffix = AA05
| ATC_supplemental =
| PubChem = 9578507
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID = 16738655
| UNII_Ref =
| UNII = A2669OWX9N
| ChEMBL_Ref =
| ChEMBL = 160777

| chemical_formula =
| C=43 | H=63 | N=1 | O=11
| molecular_weight = 769.96 g/mol
| smiles = C()1CC()2(C()3C()(O2)C/C=C(/()(()(/C=C/C=C/4\CO()\5()4(()(C=C(/C5=N/O)C)C(=O)O3)O)C)O()6C()(()(()(O6)C)O)OC)\C)O()1C7CCCCC7
| InChI = 1/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35-,37-,38-,39-,40+,42+,43+/m0/s1
| InChIKey = AFJYYKSVHJGXSN-XHKIUTQPBT
| StdInChI = 1S/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35-,37-,38-,39-,40+,42+,43+/m0/s1
| StdInChIKey = AFJYYKSVHJGXSN-XHKIUTQPSA-N
}}
Selamectin (trade names Revolution, Stronghold) is a topical parasiticide and antihelminthic used on dogs and cats, distributed by Zoetis,〔(【引用サイトリンク】title=Zoetis.com page identifying both Revolution and Stronghold as its selamectin brands )〕 a former Pfizer subsidiary. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats. It also removes 2 types of lungworm in cats (Aelurostrongylus abstrusus, Eucoleus aerophilus) and one type of lungworm in dogs (Eucoleus aerophilus). It is structurally related to ivermectin and milbemycin. Selamectin is not approved for human use.
==Usage==

The drug is applied topically. It is waterfast, and does not lose its effectiveness with bathing. It is packaged according to its varying dosage sizes, and is applied once monthly.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Selamectin」の詳細全文を読む



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