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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Seratrodast ： ウィキペディア英語版 Seratrodast Seratrodast (INN) is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist used primarily in the treatment of asthma. It was the first TP receptor antagonist that was developed as an anti-asthmatic drug and received marketing approval in Japan in 1997. Seratrodast is currently marketed in Japan,〔Bronica tablets, Takeda Pharmaceutical Co. Ltd., Japan〕 China〔Changnuo granules, Chia Tai Tianqing Pharm, China〕 and India〔Seretra tablets, Zuventus Healthcare Ltd., India〕 (approved in Dec 2012) as an add-on controller therapy in the management of asthma. Unlike thromboxane synthase inhibitors such as ozagrel, seratrodast does not affect thrombus formation, time to occlusion and bleeding time. Seratrodast has no effect on prothrombin time and activated partial thromboplastin time, thus ruling out any action on blood coagulation cascade. == Pharmacodynamics == TXA2 and other bronchoconstrictor prostanoids, like PGD2 and PGF2α, are generated in asthma and participate in acute and chronic inflammatory processes. Seratrodast, being a TP receptor antagonist, inhibits the following pathophysiological processes in asthma: 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Seratrodast」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.