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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Shelphs ： ウィキペディア英語版 Shelphs ''Shewanella''-like phosphatases, abbreviated as Shelphs, are a group of enzymes structurally related to protein serine/threonine phosphatases (PPP family). Unlike the canonical subfamilies found in eukaryotes (PP1, PP2A, calcineurin, PP5 and PPEF/PP7),〔 Shelphs span the eukaryote-prokaryote boundary and are found in several genera of proteobacteria, in plants, red algae, fungi and some unicellular parasites, including a causative agent of malaria ''Plasmodium'', ''Cryptosporidium'' and kinetoplastids (''Trypanosoma'' and ''Leishmania'' species). The prototypic member of the group, a phosphatase from a psychrophilic bacterium ''Shewanella'', has been studied as a model to understand the mechanisms that contribute to the high catalytic efficiency of enzymes from organisms adapted to low temperatures. Although PPP phosphatases in general are serine/threonine specific,〔 ''Shewanella'' phosphatase is tyrosine specific.〔 One of the two Shelph isoforms in plants is predicted to be located in the chloroplast.〔 Due to the absence of Shelphs in humans, these phosphatases have recently attracted attention as potential targets for new antiparasitic drug discovery. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Shelphs」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.