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Sigma-Tau Industrie Farmaceutiche Riunite, referred to as Sigma-Tau, emerges in 1957 from the entrepreneurial initiative of research chemist Claudio Cavazza. During a period in which multinational companies were consolidating their hegemony in the pharmaceutical sector, Claudio Cavazza conceived the idea of an industrial structure in Italy, capable of permanently competing in terms of production while at the same time bringing innovation to the field of research and pharmaceutical experimentation. Construction began in 1964 of an industrial facility in Pomezia equipped with state-of-the-art automatic production machinery to provide steady employment for 64 people. The choice of Pomezia for its headquarters created one of the first industrialization and urban development initiatives in an area of Central-southern Italy that had previously been mainly devoted to agriculture. With the creation and launch of the Rekord B12 vitamin complex in September 1966 – an antiasthenic medicine that soon spread within the field of restorative infantile therapies – Sigma-Tau definitively asserted itself as a pharmaceutical manufacturer in Italy and abroad. == From the 1970s to today == From the 1970s onwards, Sigma-Tau focused on experimenting with new medicines for rare diseases – a commitment that in 1984 would cause it to become the fourth largest pharmaceutical company in the world and assignee in the United States of an Orphan Drug Designation,〔Orphan drugs are medicines that are effective in the treatment of certain diseases that are not manufactured or put on the market due to insufficient demand to cover production costs and supply.〕 subsequently receiving another seven. With the discovery in the 1970s of carnitine deficiency syndrome, an illness with a fatal outcome, Sigma-Tau focused the investigative efforts of its laboratories on research into a molecule capable of opposing the disease. This was to bring about the creation of L-carnitine, one of the few Italian pharmaceutical products widely received outside Italy, and which was recognized by the United States in 1984 for its value as a life saving medicine. The chemical and biologic pharmacology study of carnitine, a substance of natural origin, enabled greater understanding of its efficacy in correcting the biochemical and metabolic defects at the base of numerous other pathologies. Fondazione Sigma-Tau was created in 1986 as a charitable organization with the aim of developing research, promoting scientific and cultural progress and the safeguarding of the results of scientific investigation. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Sigma-Tau」の詳細全文を読む スポンサード リンク
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