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Sinecatechins : ウィキペディア英語版
Sinecatechins

Sinecatechins (USAN, trade names Veregen and Polyphenon E) is a specific water extract of green tea leaves from ''Camellia sinensis'' that is the active ingredient in an ointment approved by the FDA in 2006 as a botanical drug to treat genital warts.〔(【引用サイトリンク】format=PDF )〕〔Masters KP (New Drug Reviews: Sinecatechins (Veregen) for External Genital and Perianal Warts ). Am Fam Physician. 2009 Dec 15;80(12):1447-1454.〕〔Fürst R, Zündorf I Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress. Mediators Inflamm. 2014;2014:146832. doi: 10.1155/2014/146832. PMID 24987194 (PMC 4060065 )〕 Sinecatechins are mostly catechins, 55% of which is epigallocatechin gallate. It was the first botanical drug approved by the US FDA.〔
The method of action of sinecatechins is undetermined. In its use for treatment of genital warts caused by the human papilloma virus, sinecatechins appear to have higher clearance rates than podophyllotoxin or imiquimod and causes less local irritation. However, clearance of lesions takes longer than with imiquimod.
== References ==


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