翻訳と辞書 Words near each other ・ Smooth-fronted caiman ・ Smooth-hound ・ Smooth-sided toad ・ Smooth-skinned forest frog ・ Smooth-toothed pocket gopher ・ Smoothback angelshark ・ Smoothback skate ・ Smoothbore ・ Smoothe ・ Smoothe da Hustler ・ Smoothed analysis ・ Smoothed finite element method ・ Smoothed maximum score estimator ・ Smoothed octagon ・ Smoothed-particle hydrodynamics ・ Smoothened ・ Smoothened agonist ・ Smoother ・ Smoother (band) ・ Smoothie ・ Smoothie King ・ Smoothie King Center ・ Smoothing ・ Smoothing (disambiguation) ・ Smoothing group ・ Smoothing plane ・ Smoothing spline ・ Smoothness ・ Smoothness (probability theory) ・ Smoothnose wedgefish Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Smoothened ： ウィキペディア英語版 Smoothened Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target of the teratogen cyclopamine. == Function == Cellular localization plays an essential role in the function of SMO. Stimulation of the patched receptor by the sonic hedgehog ligand leads to translocation of SMO to the primary cilium. Furthermore, SMO that is mutated in the domain required for ciliary localisation cannot contribute to pathway activation. SMO has also been shown to bind the kinesin motor protein Costal-2 and play a role in the localization of the Ci (Cubitus interruptus transcription factor) complex. SMO can function as an oncogene. Activating SMO mutations can lead to unregulated activation of the hedgehog pathway and cancer. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Smoothened」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.