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Spiruchostatin
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Spiruchostatin : ウィキペディア英語版
Spiruchostatin

Spiruchostatins are a group of chemical compounds isolated from ''Pseudomonas sp.'' as gene expression-enhancing substances. They possess novel bicyclic depsipeptides involving 4-amino-3-hydroxy-5-methylhexanoic acid and 4-amino-3-hydroxy-5-methylheptanoic acid residues. The two main forms are spiruchostatin A and spiruchostatin B.
== History ==
Since the early 1960s, small organic molecules derived naturally from microbes and plants have provided a number of useful cancer chemotherapeutic drugs. The search for naturally occurring lead compounds of this type has continued in recent years, with the constituents of marine fauna and flora as well as those of terrestrial microorganisms and plants being investigated for their anticancer activities. Natural products (NPs) are small molecules produced by living organisms. The term “secondary metabolite” is often used to differentiate NPs from other molecules that are synthesized in the course of primary metabolism.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Spiruchostatin」の詳細全文を読む



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