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A splenectomy is a surgical procedure that partially or completely removes the spleen. ==Indications== The spleen, similar in structure to a large lymph node, acts as a blood filter. Current knowledge of its purpose includes the removal of old red blood cells and platelets, and the detection and fight against certain bacteria. It is also known to function as a site for the development of new red blood cells from their hematopoietic stem cell precursors, and particularly in situations in which the bone marrow, the normal site for this process, has been compromised by a disorder such as leukemia. The spleen is enlarged in a variety of conditions such as malaria, mononucleosis and most commonly in cancers of the lymphatics, such as lymphomas or leukemia. It is removed under the following circumstances: #When it becomes very large such that it becomes destructive to platelets/red blood cells #For diagnosing certain lymphomas #Certain cases of wandering spleen #When platelets are destroyed in the spleen as a result of an auto-immune condition, such as idiopathic thrombocytopenic purpura. #When the spleen bleeds following physical trauma #Following spontaneous rupture #For long-term treatment of congenital erythropoietic porphyria (CEP) if severe hemolytic anemia develops #The spread of gastric cancer to splenic tissue #When using the splenic artery for kidney revascularisation in renovascular hypertension. #For long-term treatment of congenital pyruvate kinase (PK) deficiency The classical cause of traumatic damage to the spleen is a blow to the abdomen during a sporting event. In cases where the spleen is enlarged due to illness (mononucleosis), trivial activities, such as leaning over a counter or straining while defecating, can cause a rupture. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Splenectomy」の詳細全文を読む スポンサード リンク
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