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Spondyloarthropathy or spondyloarthrosis refers to any joint disease of the vertebral column.〔(thefreedictionary.com/spondyloarthropathy ) citing: *Mosby's Medical Dictionary, 8th edition. © 2009 *Miller-Keane Encyclopedia & Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 *Saunders Comprehensive Veterinary Dictionary, 3 ed. © 2007〕 As such, it is a class or category of diseases rather than a single, specific entity. It differs from spondylopathy, which is a disease of the vertebra itself. However, many conditions involve both spondylopathy and spondyloarthropathy. Spondyloarthropathy with inflammation is called ankylosing spondylitis〔Mosby's Medical Dictionary, 8th edition. © 2009〕. In the broadest sense, the term spondyloarthropathy includes joint involvement of vertebral column from any type of joint disease, including rheumatoid arthritis and osteoarthritis, but the term is often used for a specific group of disorders with certain common features, the group often being termed specifically seronegative spondylarthropathies. They have an increased incidence of HLA-B27, as well as negative rheumatoid factor and ANA. Enthesopathy is also sometimes present in association with seronegative . Nonvertebral symptoms of spondyloarthropathies include asymmetric peripheral arthritis (which is distinct from rheumatoid arthritis), arthritis of the toe interphalangeal joints, sausage digits, Achilles tendinitis, plantar fasciitis, costochondritis, iritis, and mucocutaneous lesions. However, lower back pain is the most common clinical presentation of the disease; this back pain is unique because it decreases with activity. ==Seronegative spondyloarthropathy== ''Seronegative spondyloarthropathy'' (or ''seronegative spondyloarthritis'') is a group of diseases involving the axial skeleton and having a negative serostatus. "Seronegative" refers to the fact that these diseases are negative for rheumatoid factor,〔(【引用サイトリンク】title=Seronegative Spondyloarthropathies: Joint Disorders: Merck Manual Professional )〕 indicating a different pathophysiological mechanism of disease than what is commonly seen in rheumatoid arthritis. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Spondyloarthropathy」の詳細全文を読む スポンサード リンク
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