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Spongiosis Spongiosis is mainly intercellular edema (abnormal accumulation of fluid) in the epidermis,〔Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) ''Robbins & Cotran Pathologic Basis of Disease'' (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.〕 and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification.〔Marks, James G; Miller, Jeffery (2006). ''Lookingbill and Marks' Principles of Dermatology'' (4th ed.). Elsevier Inc. Page 28. ISBN 1-4160-3185-5.〕 ==Additional images==
Image:Spongiotic_dermatitis_(2)_Dyshidrotic.JPG|Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis.
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