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Stibophen
Stibophen is an anthelmintic classified as antimony compound and used as treatment of schistosomiasis by intramuscular injection. ==Mechanism of action== Stibophen inhibits the enzyme phosphofructokinase, which the worms need for glycolysis, at least partly by binding to the sulfhydryl (–SH) group of the enzyme. Inhibiting glycolysis paralyzes the worms, which lose their hold on the wall of mesenteric veins and undergo hepatic shift, die, and are phagocytosed by liver cells.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Stibophen」の詳細全文を読む
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