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Sumanirole
Sumanirole (PNU-95,666) is a highly selective D2 receptor full agonist, the first of its kind to be discovered.〔Romero AG, et al. Synthesis of the selective D2 receptor agonist PNU-95666E from D-phenylalanine using a sequential oxidative cyclization strategy. ''Journal of Organic Chemistry''. 1997; 62(19):6582.〕 It was developed for the treatment of Parkinson's disease and restless leg syndrome. While it has never been approved for medical use it is a highly valuable tool compound for basic research to identify neurobiological mechanisms that are based on a dopamine D2-linked (vs. D1, D3, D4, and D5-linked) mechanism of action. == See also ==
* Ropinirole
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Sumanirole」の詳細全文を読む
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