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Synaptopathy : ウィキペディア英語版 | Synaptopathy
A synaptopathy is a disease relating to the dysfunction of the synapse. Examples include autism spectrum disorder, schizophrenia and Alzheimer's. Increasing knowledge of the genetic basis of these diseases has linked proteins to the function of the synapse. Age-related cochlear synaptic and neural degeneration has also been demonstrated in mice. Molecules such as FMRP1 act as translational repressor thus when ablated such as in FXS result in varying degrees of cellular and behavioural abnormalities. Additional molecules thought to be involved include SynGAP and SHANK1. ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Synaptopathy」の詳細全文を読む
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