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T-box
T-box refers to a group of transcription factors involved in limb and heart development. In humans and some other animals, defects in the TBX5 gene expression can lead to finger-like thumbs and ventricular septal defects in which there is no separation between the left and right ventricle of the heart and are responsible for Holt-Oram syndrome. TBX3 is associated with ulnar-mammary syndrome. Genes encoding T-box proteins include: * TBR1 () * TBX1 () * TBX2 () * TBX3 () * TBX4 () * TBX5 () * TBX6 () * TBX10 () * TBX15 () * TBX18 () * TBX19 () * TBX20 () * TBX21 () * TBX22 () ==See also==
* Brachyury, the first found * Homeobox * Development genes in plants: G-box, I-box, W-box, Z-box
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「T-box」の詳細全文を読む
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