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・ Tafilah, Yemen
・ Tafilalt
・ TAFIM
・ Tafingoult
・ Tafiré
・ TAFISA
・ Tafissour
・ Tafiti
・ Tafitoala
・ Tafiły
・ TAF4B
・ TAF5
・ TAF5L
・ TAF6
・ TAF6L
TAF7
・ TAF8
・ TAF9
・ TAF9B
・ Tafa
・ Tafa (disambiguation)
・ Tafa Air
・ Tafacirga
・ Tafadzwa Chitokwindo
・ Tafadzwa Dube
・ Tafadzwa Kamungozi
・ Tafadzwa Madondo
・ Tafadzwa Manyimo
・ Tafadzwa Mufambisi
・ Tafadzwa Rusike


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TAF7 : ウィキペディア英語版
TAF7

Transcription initiation factor TFIID subunit 7 also known as TAFII55 is a protein that in humans is encoded by the ''TAF7'' gene.
== Function ==

The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6879 )
The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the transcription preinitiation complex. TAFII55 binds to TAFII250 and inhibits its acetyltransferase activity. The exact role of TAFII55 is currently unknown but studies have shown that it interacts with the C-jun pathway. The conserved region is situated towards the N-terminal of the protein. This entry talks about the N-terminal domain.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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