翻訳と辞書
Words near each other
・ Tapasya Nayak Srivastava
・ Tapatalk
・ Tapatan
・ Tapatan with Jay Sonza
・ Tapatapa River
・ Tapatío
・ Tapatío hot sauce
・ Tapauá
・ Tapauá River
・ Tap wrench
・ Tap!
・ Tap, Azerbaijan
・ Tap-Out (Transformers)
・ Tap-Tap (disambiguation)
・ TAP1
TAP2
・ TaPa
・ Tapa
・ Tapa (Filipino cuisine)
・ Tapa (game)
・ Tapa Airfield
・ Tapa Army Base
・ Tapa cloth
・ Tapa Gaccha
・ Tapa Parish
・ Tapa Tchermoeff
・ Tapa, Estonia
・ TAPAAL Model Checker
・ Tapacarí
・ Tapacarí Province


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

TAP2 : ウィキペディア英語版
TAP2

TAP2 is a gene in humans that encodes the protein Antigen peptide transporter 2.
== Function ==

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2 (TAP1). The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, schizophrenia, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6891 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「TAP2」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.