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TARGIT
TARGIT (TARGeted Intra-operative radioTherapy) is a technique of giving radiotherapy to the tissues surrounding a cancer after its surgical removal. The technique was designed in 1998 at the University College London. In patients having lumpectomy for breast cancer, the TARGIT-A(lone) randomized controlled trial (recruitment from 2000-2012) tested whether TARGIT within a risk-adapted approach is non-inferior to conventional course of external beam postoperative radiotherapy given over several weeks. Over 10,000 patients have been treated with this technique in 250 centres around the world. The ongoing TARGIT-B(oost) randomized controlled trial is testing whether TARGIT tumour bed boost given after lumpectomy for breast cancer in younger patients or those with a high risk of recurrence, is superior to conventional external beam radiotherapy boost for breast cancer.
== Definition ==
TARGIT is a method where the radiation is applied during an operation and targeted to the peri-tumoural tissues. TARGIT technique was designed at University College London by Jayant S Vaidya (who coined the TARGIT acronym) and Michael Baum along with Jeffrey S Tobias in 1998. The term was first used when the technique was described, and the protocol for a randomised trial was published by the Lancet.〔(【引用サイトリンク】title=Targeted Intraoperative Radiotherapy (TARGIT)-trial protocol )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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