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TASP1 : ウィキペディア英語版
TASP1

Threonine aspartase 1 is an enzyme that in humans is encoded by the ''TASP1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55617 )
== Function ==

This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Cleavage of TFIIA has been found to drive spermatogenesis.
Alternatively spliced transcript variants have been described, but their biological validity has not been determined.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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