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・ TCCA
・ TCCC
・ TCD
・ TCDD
・ TCDD 45151 Class
・ TCDD 45171 Class
・ TCDD 46201 Class
・ Tbilissky District
・ TBJ
・ Tbjhome
・ TBK
・ TBK1
・ TBL
・ Tbl
・ TBL-37
TBL1X
・ TBL1XR1
・ TBL3
・ TBM
・ TBM-3E "Avenger" Torpedo Bomber Warplane
・ TBMM TV
・ TBN
・ TBN repeaters in the Tampa Bay DMA
・ TBN Salsa
・ TBNF
・ TBO
・ TBO (comics)
・ Tboli language
・ Tboli people
・ Tboung Khmum District


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TBL1X : ウィキペディア英語版
TBL1X

Transducin (beta)-like 1X-linked, also known as TBL1X, is a protein which in humans is encoded by the ''TBL1X'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6907 )
== Function ==

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. This gene is highly similar to the Y chromosome TBL1Y gene.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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