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''TMEM106A'' is a gene that encodes the transmembrane protein 106A (TMEM106A) in ''Homo sapiens''.〔(【引用サイトリンク】 url =http://www.ncbi.nlm.nih.gov/gene/113277 )〕 It is located at 17q21.31 on the plus strand next to cancer-related genes ''NBR1'' and ''BRCA1''.〔〔(【引用サイトリンク】 url =http://www.genecards.org/cgi-bin/carddisp.pl?gene=TMEM106A&search=tmem106a )〕 The ''TMEM106A'' gene contains a domain of unknown function, DUF1356.〔 == Protein structure == The TMEM106A protein has a molecular weight of 28.9 kdal. It has 262 amino acids, 240 of which are in the domain of function.〔 The protein has a transmembrane region. There is evidence for a secondary transmembrane region in humans but this region is not conserved in related orthologs. The protein does not contain a peptide signal protein. The protein structure contains a similar proportion of alpha-helix and beta-strand secondary structures (this does not include transmembrane structures). There are several areas for post-translational modification for TMEM106A including: : * Phosphorylation, : * N-glycosylation : * Lysine glycosylation 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「TMEM106A」の詳細全文を読む スポンサード リンク
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