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TMEM106C
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TMEM106C : ウィキペディア英語版
TMEM106C

''TMEM106C'' is a gene that encodes the transmembrane protein 106C (TMEM106C) in ''Homo sapiens'' It has been found to be overexpressed in cancer cells and also is related to Distal Arthrogryposis,〔(【引用サイトリンク】 title=Genecards )〕 a condition of stiff joints and irregular muscle development. The ''TMEM106C'' gene contains a domain of unknown function, DUF1356, that spans most of the protein. Transmembrane protein 106C also goes by the aliases ''MGC5576 or MGC111210, LOC79022''.
== Location and Gene Neighborhood ==

The TMEM106C gene is located on the long arm of the 12th chromosome. It is found at position 12q13.1. This gene spans from 48357225 to 48362667 on chromosome 12.〔 This gene is in between COL2A1, the human type II collagen gene, and VDR, the human Vitamin D Receptor gene.〔(【引用サイトリンク】date= 4 May 2014 )
This protein is found to be an integral part of the endoplasm reticulum membrane.〔(【引用サイトリンク】date= 19 Nov 1999 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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