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TMEM143
TMEM143 (Transmembrane protein 143) is a protein that in humans is encoded by TMEM143 gene.〔(【引用サイトリンク】sapiens (human) )">url=http://www.ncbi.nlm.nih.gov/gene/55260 )〕 TMEM143, a dual-pass protein (two transmembrane domains), is predicted to reside in the mitochondria〔(【引用サイトリンク】url=http://www.phosphosite.org/proteinAction.do?id=4857838&showAllSites=true )〕〔(【引用サイトリンク】url=http://www.genecards.org/cgi-bin/carddisp.pl?gene=TMEM143 )〕 and high expression has been found in both human skeletal muscle and the heart.〔(【引用サイトリンク】url=http://www.ncbi.nlm.nih.gov/geoprofiles/?term=tmem143+GDS424 )〕〔(【引用サイトリンク】url=http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&term=tmem143&submit=Go )〕 Interaction with other proteins indicate that TMEM143 could potentially play a role in tumor suppression/expression and cancer regulation.〔 ==Gene== Located on the negative strand of human DNA, TMEM143 spans 31,882 base pairs on human chromosome 19 (19q13.33), neighbored by genes Coiled-coil domain containing 114 (CCDC114) and ER lumen protein-retaining receptor 1 (KDELR1).〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「TMEM143」の詳細全文を読む
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