翻訳と辞書 |
TNK2
Activated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the ''TNK2'' gene. 〔
==Interactions== ACK1 or TNK2 has been shown to interact with AKT,〔 Androgen receptor or AR, a tumor suppressor WWOX, FYN and Grb2. ACK1 interaction with its substrates resulted in their phosphorylation at specific tyrosine residues. ACK1 has been shown to directly phosphorylate AKT at tyrosine 176, AR at Tyrosine 267 and 363, and WWOX at tyrosine 287 residues, respectively. Ack1-AR signaling has also been reported to regulate ATM levels,
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「TNK2」の詳細全文を読む
スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|