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TRIM25
Tripartite motif-containing protein 25 is a protein that in humans is encoded by the ''TRIM25'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7706 )〕
== TRIM25 functions ==
TRIM25 act in expression of IFN response. It interact with RIG-I which is a receptor from PRR (Pattern Recognitiion Receptor) family. Two domains of TRIM25 (RING and SPRY) allow an interaction with RIG-I. Thanks to this interaction an ubiquitination of RIG-I by TRIM25 is possible. Its follows an IFN production by an intracellular signaling pathway involving IRF3.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「TRIM25」の詳細全文を読む
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